6 Comments
Apr 15Liked by Owen Scott Muir, M.D

Great piece on Seroquel. Love it when you balloon the charts. Please give me the URL of the post where you explained all of them. Hard to remember not being 23 and in med school. Okay, a fundamental bi-polar treatment question. Mania is easier to treat and bring under control than depression, yes? Why then in clinical trials and office drug treatments is this overpowering emphasis on not triggering a hypomanic episode? Even to withholding a good drug from or closing a clinical trial to a bi-polar. We know the Hippocratic Oath of doing no harm. But isn't there more harm in someone wallowing in depression then getting bumped out of it by hypomania, which a little Lithium or Klonopin will tamp down easily? You probably know better drugs for that.

Expand full comment
deletedApr 15Liked by Owen Scott Muir, M.D
Comment deleted
Expand full comment