The Frontier Psychiatrists

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The Frontier Psychiatrists
Endless Medicines Don't Work for Depression
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Endless Medicines Don't Work for Depression

A new study comparing rTMS and medications again affirms its superiority

Owen Scott Muir, M.D, DFAACAP's avatar
Owen Scott Muir, M.D, DFAACAP
Aug 08, 2024
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The Frontier Psychiatrists
Endless Medicines Don't Work for Depression
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The Frontier Psychiatrists is a daily-enough health-themed newsletter. It covers effective treatments as one of our favorite beats. Recurrent Transcranial Magnetic Stimulation (rTMS) is one such approach.

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Today, we have a new paper from Dalhuisen, et. al., published in AJP in Advance, that evaluates patients with depression who have not been helped by multiple trials of medication. 1

Avid readers will recall my coverage of the ASCERTAIN-TRD trial, in which rTMS was compared to both switching antidepressant medicines or augmentation with aripiprazole after one oral antidepressant didn’t work as a first-line treatment. Short version—it’s better. By a lot:

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