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I read your article. I have BiPolar type II. Before that, my diagnosis was Major Depressive Disorder. For that I was prescribed Paxil 50-60mg. After the change in diagnosis 200mg Lamotrigene was added. To make a long story short. I'm 65, and have been living with the above since my early thirties, and probably my adolescence as well. I was prescribed antipsychotics but discontinued due to side effects. I will not consider Lithium, electro-schock etc. due to side effect profiles. I'm able to read the clinical trials, papers, literature, etc. due to my educational background. I find your article a truthful, summary based on your clinical practice, experience and review of applicable data. After living with the above , approximately for my entire life I've come to some realizations. The relief I receive from my Rxs are minimal at best. The cyclic nature, and depth of my depressive syndromes are getting more severe and intense. I have a feeling Psychedelic Rx and therapy in a clinical setting will yield some postive results for a limited amount of time, maybe 6 months to 1 year. So, I'm debating whether to go there. I'm in full agreement with your article. So far, BiPolar Disorder is lifetime, chronic and current medical treatments are at best, yielding some symptomatic relief, and clinically no more effective than placebo. I really have no choice, I have to deal with my mental illness as best I can. So, I'm still searching for symptomatic relief. Any ideas, feel free to email me at: brucedetorres@gmail.com, or call: 786-616-4978. Thanks for your article. You said it with transparent, clear facts and assessment. I think if you're able to get your article out to more widely read outlets, you will be helping many sufferers and people dealing with this terrible illness. Again thanks.

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