20 Comments
Nov 8, 2023Liked by Owen Scott Muir, M.D

I am today years old when I learned that humans can take this medicine too.... My vet gives us gabapentin fish oil for our cats to give them before their appointments so she can take blood. I thought this med was only for animals lol

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Nov 8, 2023Liked by Owen Scott Muir, M.D

Okay but it is a godsend for my cat when it’s time to go to the vet or trim nails!! Gabapentin is my favorite drug because it saves us so much stress and scratches!

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Nov 10, 2023Liked by Owen Scott Muir, M.D

At the risk of making a name for myself defending idiosyncratic drug reactions...

I find gabapentin has some anti-depressive and anti-manic properties, at least in conjunction with the rest of my regimen. Specifically my baseline is now closer to euthymic than dysthymic, and when I do get hypomanic the instances are shorter and less intense. It was prescribed for a different purpose (an anxiolytic in the context of AUD) and I was surprised by this outcome but my doc endorsed that in her experience some bipolar people find it a useful adjunct for residual symptoms, "rough edges" I think she said. The QoL increase and reduction in functional impairment were not trivial for me--those residual depressive symptoms, which didn't respond to a basketful of other treatments, were keeping me from a lot of living.

Now where's that shruggy little emoticon man so no one mistakes this for countervailing medical advice...

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Nov 9, 2023Liked by Owen Scott Muir, M.D

I remember getting gabapentin prescribed for alcohol withdrawal, and it helped so much with the shakes. But then my doctor tried to have it be a part of my mood stabilization for bipolar. That shit did NOT work haha

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Nov 8, 2023Liked by Owen Scott Muir, M.D

I'm in the UK and have been on pregabalin since 2017 for severe RLS. Neurologists consider pregabalin as the gold standard but most people in UK will never see a neurologist over RLS. Most only get as far as their GP who presecribe dopamine agonists.

I developed RLS in my 20s. It runs in my family. At 37 I was diagnosed with bipolar and given quetiapine which was like rocket fuel for my RLS. Imagine having RLS in all 4 limbs, with pain, and akithesia, and having a psychiatrist who doesn't believe in RLS and states quetiapine has no side effects. My GP managed to force my psychiatrist to prescribe something for RLS which, unfortunately, was pramipexole. Two years later I develop augmentation so the pramipexole is actually giving me RLS. I was only on .375mg max a day. It also made me psychotic and I was hospitalized because I was fixated on ending myself in a very gruesome way (which my psychiatrist brushed off by telling staff I have a weird sense of humour).

I accidentally ended up on pregabalin for RLS in the hospital. My psychiatrist cuts my pramipexole off and my RLS is left untreated for 5 days. It was horrific. It was start at midday and not let up till 7am so I did not sleep for 5 days (my psychiatrist prescribes trazadone as she now thinks I have insomnia. I don't). My psychiatrist is at a seminar by a pharma rep for pregabalin the day before she prescribes me it for the anxiety, which I don't have, but she always insists I do. But it worked wonders for RLS. Life changing.

My psychiatrist got one last kick in. I found out from my occupational health doctor at my work that my psychiatrist changed my diagnosis. Three years after being discharged from her service I found out she changed it to recurrent depression. In the 5 years I was under her "care" I was never treated for depression. Only an episode of rapid cycling which she treated with sertraline and more quetiapine both of which worsen RLS. My mother had died due to a medical error and I had a delayed and prolonged grief reaction. She thought that was recurrent depression. Although apparently I'm not significant enough for her to tell me.

As she was the one who prescribed the pregabalin I asked to be referred to neurology so that I could "protect" my prescription. Neurology wrote a seperate prescription so that I would at least keep 75mg of pregabalin. My RLS is the symptom I dread most. Some people still think it is a joke diagnosis but I could not continue without the pregabalin. I already had RLS but that woman has left me with this superjacked version if this atrocious condition.

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Nov 8, 2023Liked by Owen Scott Muir, M.D

More on gabapentin and menopause symptoms… https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076904/

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Nov 8, 2023Liked by Owen Scott Muir, M.D

It does appear to work for perimenopausal and menopause symptoms at night… particularly for women with breast cancer who cannot take hormones. We have seen good success with hot flash reduction and night sweats.

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