There are some days when you just…can’t. Can’t anything. This is one of those days, and writing an article about Celexa (Citalopram) is, ironically, one of those things. As we will see, this is also dark humor of the foreshadowing variety. Welcome to The Frontier Psychiatrists, a health-themed publication edited by Owen Scott Muir, M.D., DFAACAP.
My book is Inessential Pharmacology. (amazon link) and contains many chapters like this article…consider reading it!
Citalopram is a selective serotonin reuptake inhibitor (SSRI). I’ve already covered why even this name is a lie: in animal models without the serotonin transporter gene, which codes for the protein that is the putative site of pharmacological action for these medicines, they still work just fine1. This means it can’t be the selective serotonin-ness of the SSRI medications that is responsible for their effects. It’s a bit like if doors were assumed to only open because of the twisting of the knob, and then someone made a doo…