We don't have data that I'm aware of that would answer this question. However, "reversible damage" tends to be the rule in metabolic health. People gain weight, and they can lose weight, They can have increased cholesterol, or reduced cholesterol, and all of us are dead over long enough time scale.
Can you further explain metabolic syndrome?
https://open.substack.com/pub/thefrontierpsychiatrists/p/an-inconvenient-truth-about-the-mental?r=1ct8f&utm_campaign=post&utm_medium=web
These two articles are probably my best on the topic.
https://open.substack.com/pub/thefrontierpsychiatrists/p/metabolic-syndrome-is-a-real-illness?r=1ct8f&utm_campaign=post&utm_medium=web
Do metabolic conditions continue even if you get off of these medications after (6 months) or is it irreversible damage?
We don't have data that I'm aware of that would answer this question. However, "reversible damage" tends to be the rule in metabolic health. People gain weight, and they can lose weight, They can have increased cholesterol, or reduced cholesterol, and all of us are dead over long enough time scale.
To be clear, are you saying Wellbutrin is completely neutral / does not impact weight?
That is what the data suggests
Trying to gauge safety
For metabolic safety, among oral medicines, bupropion is the safest option--it's also very much not anxiety reducing , unlike most of the others