How Big of A Deal Are Psychedelic Medicines Likely to Be?

We ask a meta-analysis and an AI Image generator.

The Frontier Psychiatrists strives for a world where health-themed newsletter writing can be at once “funny” and “hip-hop-informed” in a way that makes health-related science more comprehensible. Today, we are trying something new. Yes, that is the royal We. Although We (Owen Muir, M.D., DFAACAP, unless otherwise noted) author this newsletter the old-fashioned way—with bespoke typos and spelling errors to indicate there is no AI Bot cranking out the remarkable amount of writing by any human standard on these digital pages…We are not about using an AI image generator to make a silly point.

I have previously argued for the “Skee-Lo Standard” (using the Muir-Skee-Lo Emotionally Corrective Equation) in which Effect Size is converted into “height differences.” Effect Size (ES) is in units of standard deviations. The SD of the height of the American Male Human is 2.5 inches. Thus, the MS-L EQE takes the ES (sometimes reported as Standard Mean Difference or SMD) and multiplies it by 2.…