The Frontier Psychiatrists

The Frontier Psychiatrists

Share this post

The Frontier Psychiatrists
The Frontier Psychiatrists
Deep Brain Stimulation (DBS) For Obsessive Compulsive Disorder (OCD)

Deep Brain Stimulation (DBS) For Obsessive Compulsive Disorder (OCD)

It's Not Exactly Brain Surgery, other than being literal brain surgery.

Owen Scott Muir, M.D, DFAACAP's avatar
Owen Scott Muir, M.D, DFAACAP
Feb 09, 2025
∙ Paid
9

Share this post

The Frontier Psychiatrists
The Frontier Psychiatrists
Deep Brain Stimulation (DBS) For Obsessive Compulsive Disorder (OCD)
2
Share

The Frontier Psychiatrists is a daily health-themed newsletter. Today, I'm doing a little bit of an overview about a treatment modality that I don't provide.

There are two noble prizes in Psychiatry, for interventions. The first was awarded to Julius Wagner-Jauregg, M.D., in 1927 for the development of malaria therapy for the treatment of neurosyphilis, or “general paresis of the insane.”

Yes, we gave people malaria as a treatment for insanity. It turns out that syphilis is caused by the parasite Treponema palladium, dies at a temperature of 104°F, and malaria, another parasitic infection, creates waxing and waning fevers, that get up to 105°F. And so, if you're able to infect somebody who happens to have neurosyphilis, those spirochetes in the brain, with malaria, the temperature will get so high that it's a biological treatment that kills the bugs that was making individuals insane. In the early part of the 20th century, when Warner-Jauregg developed this treatment modality, it…

This post is for paid subscribers

Already a paid subscriber? Sign in
© 2025 The Frontier Psychiatrists
Privacy ∙ Terms ∙ Collection notice
Start writingGet the app
Substack is the home for great culture

Share